Creating the Mac and Cheese Meatloaf Casserole is as easy as following these simple steps:

1. Preheat the Oven: Begin by preheating your oven to 350°F (175°C).
2. Mix Ingredients: In a large mixing bowl, combine ground beef, cooked macaroni, shredded cheddar cheese, breadcrumbs, milk, ketchup, egg, onion powder, garlic powder, salt, and pepper. Mix until thoroughly combined.
3. Transfer to Casserole Dish: Lightly grease a casserole dish, then pour the mixture into the dish, spreading it evenly.
4. Add Topping: Sprinkle the additional cheese over the top of the casserole.
5. Bake: Place the casserole in the oven and bake for 50–60 minutes, or until the meatloaf is cooked through and the cheese is bubbly and golden.
6. Let Rest: Once baked, remove the casserole from the oven and let it rest for about 10 minutes to set.
7. Garnish: If desired, sprinkle freshly chopped parsley over the top before serving.

Following these straightforward instructions will lead you to a successful and delicious casserole that will delight everyone at your table.